Baier NF, Miao M, Schirrmacher R, Wängler B, Fricker G, Wängler C* (2026) New Synthetic Strategies toward DFO*: Enhanced Yield and Purity of a Key Chelator for 89Zr Chemistry. Pharmaceuticals, 19(6), 813.DOI: 10.3390/ph19060813. Abstract Background: Zirconium-89 (89Zr) is a key PET radionuclide and the limited in vivo stability of its clinically used 89Zr-DFO complexes has driven the
... read moreBaier NF, Cieslik P, Rudolf H, Pretze M, Wängler B, Schirrmacher R, Greb L, Fricker G, Varga Z, Kovács A*, Wängler C* (2026) Macropa Scaffold Expansion for Actinium-225 Chelation: Synthetic Strategy, Labeling Kinetics, and Theoretical Calculations. Inorganic Chemistry, 65(18), 9769–9786.DOI: 10.1021/acs.inorgchem.5c05424. Abstract 225Ac is a key α-emitter for targeted alpha therapy. Among available chelators, Macropa currently
... read moreZierke MA, Hofer K, Samadikhah K, Rangger C, Wängler C, Wängler B, Junker A, Schmid AM, Haubner R (2026) Comparison of two 18F-Fluorinated Glycopeptides for PET Imaging of the Functional Liver Mass. EJNMMI Radiopharmacy and Chemistry, 11(1), 35.DOI: 10.1186/s41181-026-00445-z. Abstract Background: The non-invasive determination of the asialoglycoprotein receptor (ASGR) expression on liver tissue might be a predictive
... read moreAnne Adlung, Niklas Westhoff, Daniel Hausmann, Stefan O Schoenberg, Dominik Nörenberg, Frank G Zöllner, Fabian Tollens (2026) Decreased Tissue Sodium Concentration in Suspected Prostate Cancer Detected by Internal-Reference 23Na MRI: A Prospective Exploratory Study. Medical Imaging and Theranostics.DOI: 10.3390/diagnostics16071064 Abstract Purpose: To evaluate Sodium Magnetic Resonance (23Na MR) images of prostate cancer (PCa) and quantify tissue sodium concentration (TSC) based on internal references. Methods: Forty-six
... read moreDonabauer M, Sawall S, Ayx I, Wängler C*, Schoenberg SO, Wängler B* (2026) Development and Characterization of New Contrast Agents for Photon-Counting CT. European Journal of Radiology, 195, 112643. DOI: DOI: 10.1016/j.ejrad.2025.112643. Abstract Purpose: The development of novel contrast agents is a critical step in unleashing the full potential of Photon-Counting Computed Tomography (PCCT), as clinically approved
... read moreRoll W,Hadjitheodorou P, Alevroudis E, Kyrou K, Adamou G, Fesas A, Wängler B, Wängler C, Schirrmacher R, Pourkhessalian MR, Kalogirou C, Tsechelidis I, Vrachimis A (2026) Head to head comparison of [18F]SiTATE versus [18F]DOPA-PET in patients with neuroendocrine tumors. European Journal of Nuclear Medicine and Molecular Imaging, 53(3), 1803–1810.DOI: 10.1007/s00259-025-07572-w. Abstract Background: In neuroendocrine tumors molecular imaging
... read moreMansour N, JoramJ, Grawe F, Hinterberger A, Rübenthaler J, Kunz WG, Winkelmann M, Cyran CC, Ricke J, Öcal O, Unterrainer M, Jurkschat K, Wängler C, Wängler B, Schirrmacher R, Nitschmann A, Greve T, Sheikh G, Holzgreve A, Albert NL, Fabritius MP (2025) Validation of SUV Thresholds in [¹⁸F]SiTATE PET/CT for Accurate Meningioma Segmentation. European Journal
... read moreP. Schülein, N. Rettig, L. Marxen, N. Rathmann, S. Diehl, M. Vetter, “A modular AI-supported dosimetry system for real-time scatter radiation monitoring and visualization in hybrid operating rooms”, CARS 2025—Computer Assisted Radiology and Surgery Proceedings of the 39th International Congress and Exhibition Berlin, Germany, June 17–20, 2025. Int J CARS 20 (Suppl 1), 1–115 (2025). https://doi.org/10.1007/s11548-025-03373-6
... read moreA. Meyer, N. Rathmann, S. Diehl, M. Vetter, “AI-driven interactive avatars for supporting communication in clinical and preoperative settings”, CARS 2025—Computer Assisted Radiology and Surgery Proceedings of the 39th International Congress and Exhibition Berlin, Germany, June 17–20, 2025. Int J CARS 20 (Suppl 1), 1–115 (2025). https://doi.org/10.1007/s11548-025-03373-6
... read moreGower-Fry L, Bailey JJ, Wuest M, Pike S, Kostikov A, Dorian A, Wängler C, Wuest F, Schirrmacher R (2025) Development and Clinical Potential of 18F-PSiMA for Prostate Cancer PET Imaging. RSC Medicinal Chemistry, 16(8), 3633–3644. DOI: 10.1039/d5md00275c. Abstract Prostate-specific membrane antigen (PSMA) is a key target for diagnosing prostate cancer through positron emission tomography (PET).
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