Publikationen


Decreased Tissue Sodium Concentration in Suspected Prostate Cancer Detected by Internal-Reference 23Na MRI: A Prospective Exploratory Study

01.04.2026

Anne Adlung, Niklas Westhoff, Daniel Hausmann, Stefan O Schoenberg, Dominik Nörenberg, Frank G Zöllner, Fabian Tollens (2026) Decreased Tissue Sodium Concentration in Suspected Prostate Cancer Detected by Internal-Reference 23Na MRI: A Prospective Exploratory Study. Medical Imaging and Theranostics.DOI: 10.3390/diagnostics16071064 Abstract Purpose: To evaluate Sodium Magnetic Resonance (23Na MR) images of prostate cancer (PCa) and quantify tissue sodium concentration (TSC) based on internal references. Methods: Forty-six

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Cohort-Scale Spatial Autocorrelation for Tumor Prediction in Mid-Infrared Pathology and Spatial Biomarker Discovery Using MALDI Imaging Lipidomics

09.02.2026

M. F.Rittel, N.Ebert, D.Abu Sammour, et al. “Cohort-Scale Spatial Autocorrelation for Tumor Prediction in Mid-Infrared Pathology and Spatial Biomarker Discovery Using MALDI Imaging Lipidomics.” Advanced Science13, no. 24 (2026): e16847DOI: https://doi.org/10.1002/advs.202516847 Abstract Mid-infrared (MIR) imaging is an emerging label-free modality for classifying tissue types, including viable tumor in highly heterogeneous cancers, by assessing spatial differences

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Validation of SUV thresholds in [¹⁸F]SiTATE PET/CT for accurate meningioma segmentation

23.07.2025

Mansour N, JoramJ, Grawe F, Hinterberger A, Rübenthaler J, Kunz WG, Winkelmann M, Cyran CC, Ricke J, Öcal O, Unterrainer M, Jurkschat K, Wängler C, Wängler B, Schirrmacher R, Nitschmann A, Greve T, Sheikh G, Holzgreve A, Albert NL, Fabritius MP (2025) Validation of SUV Thresholds in [¹⁸F]SiTATE PET/CT for Accurate Meningioma Segmentation. European Journal

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A modular AI-supported dosimetry system for real-time scatter radiation monitoring and visualization in hybrid operating rooms

29.05.2025

P. Schülein, N. Rettig, L. Marxen, N. Rathmann, S. Diehl, M. Vetter, „A modular AI-supported dosimetry system for real-time scatter radiation monitoring and visualization in hybrid operating rooms“, CARS 2025 — Computer Assisted Radiology and Surgery Proceedings of the 39th International Congress and Exhibition Berlin, Germany, June 17–20, 2025. Int J CARS 20 (Suppl 1), 1–115

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AI-driven interactive avatars for supporting communication in clinical and preoperative settings

29.05.2025

A. Meyer, N. Rathmann, S. Diehl, M. Vetter, „AI-driven interactive avatars for supporting communication in clinical and preoperative settings“, CARS 2025—Computer Assisted Radiology and Surgery Proceedings of the 39th International Congress and Exhibition Berlin, Germany, June 17–20, 2025. Int J CARS 20 (Suppl 1), 1–115 (2025). https://doi.org/10.1007/s11548-025-03373-6

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Development and Clinical Potential of 18F-PSiMA for Prostate Cancer PET Imaging

09.05.2025

Gower-Fry L, Bailey JJ, Wuest M, Pike S, Kostikov A, Dorian A, Wängler C, Wuest F, Schirrmacher R (2025) Development and Clinical Potential of 18F-PSiMA for Prostate Cancer PET Imaging. RSC Medicinal Chemistry, 16(8), 3633–3644. DOI: 10.1039/d5md00275c. Abstract Prostate-specific membrane antigen (PSMA) is a key target for diagnosing prostate cancer through positron emission tomography (PET).

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Structured reporting of neuroendocrine tumors in PET/CT using [18F]SiTATE – impact on interdisciplinary communication

08.02.2025

Hinterberger A, Trupka L, Kortbein S-V, Ebner R, Fink N, Frölich M, Nörenberg D, Wängler C, Wängler B, Schirrmacher R, Holzgreve A, Brendel M, Corradini M, Auernhammer C, Rübenthaler J, Grawe F (2025) Structured Reporting of Neuroendocrine Tumors (NET) in PET/CT using [18F]SiTATE – Impact on Quality and Interdisciplinary Communication. Scientific Reports, 15(1), 4793.DOI: 10.1038/s41598-025-88999-x Abstract

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EAGLE: an edge-aware gradient localization enhanced loss for CT image reconstruction

30.01.2025

Yipeng Sun, Yixing Huang, Zeyu Yang, Linda-Sophie Schneider, Mareike Thies, Mingxuan Gu, Siyuan Mei, Siming Bayer, Frank G. Zöllner, and Andreas Maier „EAGLE: an edge-aware gradient localization enhanced loss for CT image reconstruction,“ Journal of Medical Imaging 12(1), 014001 (22 January 2025). https://doi.org/10.1117/1.JMI.12.1.014001 Purpose We aim to enhance deep learning-based computed tomography (CT) image reconstructions.

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Are 3D Tumor Cell Spheroids a Utile System for the In Vitro Evaluation of Diagnostic Radiotracers?

16.12.2024

Judmann B, Keller F, Wängler B, Schirrmacher R, Rudolf R, Wängler C* (2024) Are 3D tumor cell spheroids a utile system for the in vitro evaluation of diagnostic radiotracers? ACS Omega, 9(52), 51349–51362. DOI: 10.1021/acsomega.4c08214. Abstract: By possibly bridging the gap between 2D in vitro cell assays and in vivo applications, tumor cell spheroid cultures offer promising avenues for

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Truncated NPY-based NPY(Y1)R-specific radiopeptides: Improved in vivo PET tumor imaging by application of peptidase inhibitors

01.12.2024

Judmann B, Baier NF, Rudolf H, Davarci G, Wängler B, Schirrmacher R, Fricker G, Wängler C* (2024). Truncated NPY-based NPY(Y1)R-specific radiopeptides: Improved in vivo PET tumor imaging by application of peptidase inhibitors. European Journal of Medicinal Chemistry Reports, 12, 100223.https://doi.org/10.1016/j.cellin.2024.100223DOI: 10.1016/j.cellin.2024.100223 Abstract The neuropeptide Y receptor subtype 1 (NPY(Y1)R) exhibits high expression rates on human breast cancer

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