3D Histograms of Oriented Gradients zur Registrierung von regulären CT mit interventionellen CBCT Daten


Trimborn B, Wolf I, Abu-Sammour D, Henzler T, Schad LR, Zöllner FG Bildverarbeitung für die Medizin 2017; pp 154-154

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Computed Tomography-Assisted Thoracoscopic Surgery: A Novel, Innovative Approach in Patients With Deep Intrapulmonary Lesions of Unknown Malignant Status.


Kostrzewa M, Kara K, Rathmann N, Tsagogiorgas C, Henzler T, Schoenberg SO, Hohenberger P, Diehl SJ, Roessner ED. Invest Radiol. 2017 Jan 30. doi: 10.1097/RLI.0000000000000353. [Epub ahead of print] Abstract OBJECTIVES: Minimally invasive resection of small, deep intrapulmonary lesions can be challenging due to the difficulty of localizing them during video-assisted thoracoscopic surgery (VATS). We

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Treatment planning in PRRT based on simulated PET data and a PBPK model. Determination of accuracy using a PET noise model.


Hardiansyah D, Guo W, Attarwala AA, Kletting P, Mottaghy FM, Glatting G. Treatment planning in PRRT based on simulated PET data and a PBPK model. Determination of accuracy using a PET noise model. Nuklearmedizin. 2017;56(1):23-30. doi: 10.3413/Nukmed-0819-16-04. AbstractAIM:To investigate the accuracy of treatment planning in peptide-receptor radionuclide therapy (PRRT) based on simulated PET data (using

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The role of patient-based treatment planning in peptide receptor radionuclide therapy.


Hardiansyah D, Maass C, Attarwala AA, Müller B, Kletting P, Mottaghy FM, Glatting G Eur J Nucl Med Mol Imaging. 2016 May;43(5):871-80. doi: 10.1007/s00259-015-3248-6. Epub 2015 Nov 18. Abstract BACKGROUND: Accurate treatment planning is recommended in peptide-receptor radionuclide therapy (PRRT) to minimize the toxicity to organs at risk while maximizing tumor cell sterilization. The aim

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Time-integrated activity coefficient estimation for radionuclide therapy using PET and a pharmacokinetic model: A simulation study on the effect of sampling schedule and noise.


Hardiansyah D, Guo W, Kletting P, Mottaghy FM, Glatting G Med Phys. 2016 Sep;43(9):5145. doi: 10.1118/1.4961012. Abstract PURPOSE: The aim of this study was to investigate the accuracy of PET-based treatment planning for predicting the time-integrated activity coefficients (TIACs). METHODS: The parameters of a physiologically based pharmacokinetic (PBPK) model were fitted to the biokinetic data

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Radiation Dose Comparison Between 70 kVp and 100 kVp With Spectral Beam Shaping for Non-Contrast-Enhanced Pediatric Chest Computed Tomography: A Prospective Randomized Controlled Study.


Weis M, Henzler T, Nance JW Jr, Haubenreisser H, Meyer M, Sudarski S, Schoenberg SO, Neff KW, Hagelstein C Invest Radiol. 2017 Mar;52(3):155-162. doi: 10.1097/RLI.0000000000000325. PMID: 27662576 DOI: 10.1097/RLI.0000000000000325

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Scores for standardization of on-tissue digestion of formalin-fixed paraffin-embedded tissue in MALDI-MS imaging


Erich K, Sammour DA, Marx A, Hopf C. Biochim Biophys Acta. 2016 Sep 6. pii: S1570-9639(16)30182-0. doi: 10.1016/j.bbapap.2016.08.020. Abstract On-slide digestion of formalin-fixed and paraffin-embedded human biopsy tissue followed by mass spectrometry imaging of resulting peptides may have the potential to become an additional analytical modality in future ePathology. Multiple workflows have been described for

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Design of a multimodal (1H/23Na MR/CT) anthropomorphic thorax phantom


Neumann W, Lietzmann F, Schad LR, Zoellner FG Zeitschrift für Medizinische Physik, Available online 2 September 2016, ISSN 0939-3889, AbstractObjectivesThis work proposes a modular, anthropomorphic MR and CT thorax phantom that enables the comparison of experimental studies for quantitative evaluation of deformable, multimodal image registration algorithms and realistic multi-nuclear MR imaging techniques. MethodsA human

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A novel approach for a 2D/3D image registration routine for medical tool navigation in minimally invasive vascular interventions.


Schwerter M, Lietzmann F, Schad LR. Z Med Phys 2016 Sep 2;26(3):259-69. Epub 2016 May 2. AbstractMinimally invasive interventions are frequently aided by 2D projective image guidance. To facilitate the navigation of medical tools within the patient, information from preoperative 3D images can supplement interventional data. This work describes a novel approach to perform a

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Inhibition of Rho-Associated Kinase 1/2 Attenuates Tumor Growth in Murine Gastric Cancer


Hinsenkamp I, Schulz S, Roscher M, Suhr AM, Meyer B, Munteanu B, Fuchser J, Schoenberg SO, Ebert MP, Wängler B, Hopf C, Burgermeister E Neoplasia. 2016 Aug;18(8):500-11. doi: 10.1016/j.neo.2016.07.002 Gastric cancer (GC) remains a malignant disease with high mortality. Patients are frequently diagnosed in advanced stages where survival prognosis is poor. Thus, there is high

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